Journal of Computational Systems Biology

Dr. Jie Zheng is a tenure-track assistant professor of School of Computer Engineering, Nanyang Technological University (NTU), Singapore, and an adjunct faculty (senior research scientist) of Genome Institute of Singapore (GIS). He received Ph.D. in 2006 from the University of California, Riverside and his B. Eng (first class honors) in 2000 from Zhejiang University in China, both in Computer Science. Before joining NTU in 2011, he was a research scientist at the National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), USA. While trained as a Computer Scientist, Dr. Zheng maintains active and long-standing collaborations with Life Scientists.

In the age of “big data” for biomedicine, computational technologies play ever more important roles in life sciences. The objectives of my research consist of: (1) developing computational methods to analyze the data from biomedical research, to understand the mechanisms of human diseases; (2) building integrative and predictive models that can recapitulate phenomena observed in wet-lab experiments; (3) using the models to predict behaviors of living systems under different conditions, thereby facilitating the discovery of novel therapeutics and healthcare solutions. Currently my group works on the following areas: (1) Computational genomics and systems biology in human disease study (cancer and malaria); (2) epigenetic regulation of gene expression; (3) in silico modeling of cell fate for cancer and stem cell research.