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Recent Articles

Immunity to Anaplasma marginale and Recent Advances in Vaccine Development

Anaplasma marginale is the etiological agent of bovine anaplasmosis, one of the most prevalent tick-borne diseases of cattle in tropical and subtropical regions that causes significant economic losses to cattle industry. Cattle that survive infection remain persistently infected for life. Immunity against A. marginale infection seems to require both humoral and cellular mechanisms. Antibodies against A. marginale neutralize bacteria by interacting with Major Surface Proteins (MSPs). For this reason, MSPs are believed to be one of the best candidate antigens for vaccine development. Research carried out in the last few years has helped us to understand the antigenic composition of A. marginale and to develop new potential vaccine formulations. Desirable bovine anaplasmosis vaccine must induce protective immunity as well as prevent infection and transmission

The Sensory Attributes Potentiating Effect of Mid-Infrared Rays on Moringa Leaf

Moringa leaf (Moringa oleifera) is referred to as the “natural nutrition of the tropics”, and in the Philippines, as “mothers’ best friend”. It possesses many health benefits and is also used in disease prevention and therapy. The enhancement of moringa’s natural potency is a scientific challenge that has yet to be thought of. We found enhanced inherent characteristics in the moringa leaf by irradiating using our recently invented 2-6µm mid-infrared ray generating atomizer (MIRGA). The achieved benefits were a more desirable taste and aroma, and an enhanced shelf life, thus increasing the potential transportation distance, quality, and palatability. This scientific achievement was supported by suitable instrumentations and sensory evaluation

Formulation and Evaluation of Clindamycin Peel-Off Gel Face Mask against Acne Vulgaris

The main aim of this project is to formulate and evaluate Clindamycin peel-off gel face mask against Acne vulgaris. Peel off gel mask of Clindamycin phosphate was formulated using different excipients like Triethanolamine, Carbopol, Polyvinyl Alcohol, Glycerine, Xanthan gum, and Benzyl alcohol. Formulation of different composition of polymer was formulated and their pH, extrudability, homogeneity, spreadability, viscosity, washability and other parameters like drug content, permeability and drug release were evaluated. The result showed that the concentration of PVA and Carbopol which are the main polymers used in the formulations had effect on the drug content, drug release, permeability, spreadability and other parameters. The peel off mask prepared by using different concentration of these two polymers showed satisfactory result in all the evaluated parameters.

The Development of a Classification System for the Treatment of Scoliosis by the Side Shift Approach

The Side Shift approach to correction of scoliosis curves has been used by therapist at the Royal National Orthopaedic Hospital (RNOHT) for over 30 years. The Side Shift approach was developed by Mrs Min Mehta, and has been Modified using consensus based evidence of SOSORT. Clinical observations had indicated that not all patients could actively (Auto) correct to beyond the trunk midline, a key principle of Side Shift. At the RNOHT a classification system based upon the ability of an individual to auto-correct the spine during a Side Shift movement has been developed to aid the appropriate application of the shift exercises and allow future comparative analysi