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    Annex publishers is an Open Access publication model which allows the publication of articles to the world through this community. We provide you the asset of interaction with the most researchers from the scientific community. Anyone can freely access the articles printed under Annex publishers.
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    Open access provides an unlimited access to journals and publications, with a perfect platform for thousands of researchers to form jointly for the development of science. Open Access assists in accelerating the scientific discovery, encourage innovation, enhance education and refresh the economy to build up the knowledge of the general public.
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Recent Articles

A Selected Case of Achalasia Treated with Botulinum Toxin Case Presentation

There is presented intrasphincetric injection management of achalasia, an esophageal dysmotility disorder involving an abnormal relaxation of the lower esophageal sphincter. Botulinum toxin A is a well-described treatment for achalasia, in patients who is contraindicated others modality due to comorbidity, especially in older age. We describe a case of a successful treatment of achalasia in the 83-old man with botulinum toxin A, as efficacy and very safe method for symptomatic relieve of these patients.

CCR5 Promoter SNP Genotype in HIV Seropositive Infants on Combination Antiretroviral Therapy in Uganda: Association with Virological Failure

According to the UNAIDS 2022 report, 52% of the HIV positive children between 0-14 years were able to access treatment and of these 68% attain viral suppression. CCR5 promoter genotype specifically single nucleotide polymorphisms have been linked to modulate patient virological status. However, the few studies that have studied the association in infants have utilized allele-specific PCR a genotypic method limited to detecting already known SNPs. By using Sanger sequencing, we explored the association taking into account novel mutations.