- Endothelial Cells May Have Tissue-Specific Origins
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
Home Medicines Review (HMR) is an Australian initiative introduced in 2001 to improve quality use of medicines. Medication management services such as HMRs have the potential to reduce medication related problems.
Enhancing Tissue Engineering/Regenerative Medicine Product Commercialization: The role of science in regulatory decision making for TE/RM product development
In 2010, the TERMIS-AM Industry Committee (TERMIS-AM/IC) began to delineate potential opportunities to enhance commercialization of products highlighted by the TERMIS constituency.
Immunomodulatory anticancer drugs, such as the anti-programmed death-1 drug pembrolizumab, have shown promising results in trials, and more patients will receive such treatments. Little is known about cutaneous adverse events (AEs) caused by these drugs and their possible correlation with treatment response.
Nanoparticles for inhibition of in vitro tumour angiogenesis: synergistic actions of ligand function and laser irradiation
Careful design of nanoparticles plays a crucial role in their biomedical applications. It not only defines the stability of nanoparticles in a biological medium but also programs their biological functionality and specific interactions with cells.
Association of metabolic complications with plasma mid-regional pro-adrenomedullin level in stable kidney transplant recipients
Recently, increased plasma mid-regional pro-adrenomedullin (MR-proADM) concentrations have been demonstrated in patients with chronic renal failure. In this study, we attempted to identify significant clinical factors associated with MR-proADM concentration in stable kidney transplant recipients.
New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr-/- mice
Peroxisome proliferator-activated receptor gamma (PPARγ) regulates multiple pathways involved in the pathogenesis of obesity and atherosclerosis. Here, we evaluated the therapeutic potential of GQ-177, a new thiazolidinedione, on diet-induced obesity and atherosclerosis.
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by releasing vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO) which activates soluble guanylyl cyclase in the vascular smooth muscle cells, with the production of cyclic huanosine monophosphate (cGMP) initiating relaxation.
An in vitro study of mucoadhesion and biocompatibility of polymer coated liposomes on HT29-MTX mucus-producing cells
Drug delivery to the oral cavity poses a significant challenge due to the short residence time of the formulations at the site of action. From this point of view, nanoparticulate drug delivery systems with ability to adhere to the oral mucosa are advantageous as they could increase the effectiveness of the therapy.
Scientists have always been trying to use artificial zeolites to make modified release drug delivery systems in the gastrointestinal tract. An ideal carrier should have the capability to release the drug in the intestine, which is the main area of absorption. Zeolites are mineral aluminosilicate compounds with regular structure and huge porosity, which are available in natural and artificial forms.
The use of recombinant elastin-like materials or elastin-like recombinamers (ELRs), in drug-delivery applications is reviewed in this work. Although ELRs were initially used in similar ways to other, more conventional kinds of polymeric carriers, their unique properties soon gave rise to systems of unparalleled functionality and efficiency.
Migraine is a highly prevalent neurovascular disorder in the brain. An optimal therapy for migraine has not yet been developed. Gastrodin (Gas), the main effective constitute from Gastrodiae Rhizoma (Tianma in Chinese), has been indicated for migraine treatment and prophylaxis more than 30years, with demonstrated safety.
Journal of Pharmaceutics & Drug Development
Journal of Pharmaceutics and Drug Development (JPDD) is an international peer-reviewed open access journal dedicated to provide the improvement and propagation of scientific knowledge on pharmaceutics and drug development and also related academic disciplines. JPDD aims to deliver quality work and access to its readers across various fields of science. All articles are peer reviewed and published under the guidance of our Editorial Board members.
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