Journal of Biochemistry and Biophysics

Editorial Board Member - JBB

Jianfei Qi

Assistant Professor
Biochemistry and Molecular Biology
University of Maryland School of Medicine
United States

Dr. Jianfei Qi got his Ph.D. degree in biochemistry at University of Toronto. His thesis work was under direction of Dr. Chi-Hung Siu, and focused on role of N-cadherin and b-catenin signaling in the transendothelial migration of cancer cells, an important step in the cancer metastatic cascade. He joined Dr. Ze’ev Ronai’s laboratory at Sanford-Burnham Medical Research Institute as a postdoctoral fellow and then as a staff scientist. His postdoctoral work identified a key role for the E3 ubiquitin ligase Siah2 in the neuroendocrine differentiation and castration resistance of human prostate cancer via the regulation of hypoxia-inducible factor (HIF-1a) and androgen receptor (AR) pathways, respectively. He was establishing his own laboratory at University of Maryland School of Medicine and will further investigate the mechanisms of Siah2 and histone demethylase Jmjd1a in the prostate cancer biology.


Dr. Jianfei Qi research interest is to elucidate the mechanisms by which the E3 ubiquitin ligase Siah2, histone demethylase Jmjd1a and their downstream effectors influence two major phenotypes associated with the more advanced forms of prostate cancer (PCa) – castration-resistant prostate cancer (CRPC) and neuroendocrine differentiation (NED). His previous work has begun to identify the molecular mechanisms by which Siah2 promotes castration resistance, which provide initial insight into the role of Siah2 on CRPC and NED via regulation of androgen receptor (AR) and hypoxia-inducible factor (HIF), respectively. Further investigation of the mechanisms by which Siah2 and Jmjd1a regulate their downstream signaling in prostate cancer models will likely lead to novel markers and targets for the diagnosis, monitoring, and treatment of aggressive prostate cancer in the future.  

Other Editorial Board Members - JBB

Martin Falk

Head and Professor
Institute of Biophysics of ASCR
Czech Republic


Associate Professor
Department of Biophysics
Yerevan State University

Maria Amália da Silva Jurado

Assistant Professor
Department of Life Sciences
University of Coimbra


Associate Professor
Chair of Physical and Colloidal Chemistry
Yerevan State University

Elmar J Prenner

Assistant Professor
Department of Biological Sciences
University of Calgary

Hironao Wakabayashi

Assistant Professor
Department of Biochemistry & Biophysics
University of Rochester
United States

Songon An

Assistant Professor
Department of Chemistry and Biochemistry
University of Maryland Baltimore County
United States

Junjie Zhang

Department of Biochemistry and Biophysics
Texas A&M Univeristy
United States

Liqing Yu

Associate Professor
Departments of Animal and Avian Sciences
University of Maryland
United States

Vladimir Morozov

Chair of Molecular Physics
Yerevan State University
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