Staphylococcus aureus and Staphylococcus epidermidis are major agents of nosocomial infections and exhibit high levels of antimicrobial resistance. e CRISPR/Cas system functions as a bacterial defense mechanism against mobile genetic elements, such as phages and plasmids, and may be the acquisition of resistance genes. s study aimed to investigate the presence, diversity, and functional implications of the CRISPR/Cas system in complete genomes of S. aureus and S. epidermidis, including its relationship with integrated bacteriophages, anti-CRISPR genes, and antimicrobial resistance genes. A total of 30 complete genomes from each species were analyzed, all retrieved from the NCBI database
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Recent Articles
Keto-Enol Tautomerism and Anticancer Potential on Sudan Blue II and Synthesis and Characterisation of Sudan Blue II / Cyclodextrin doped ZnO Nanocrystals
Sudan blue II/cyclodextrin doped zinc oxide nanoparticles are synthesized and characterized by various spectral and micros
copic methods. The doping effect of SBII/CD on ZnO nano was investigated by UV-visible, fluorescence, FTIR, DTA, XRD,
FE-SEM, and TEM methods. Nanoparticle size was measured by TEM-EDS and X-RD methods. The effect of different po
larities of the solvents, α-cyclodextrin (α-CD) and β-cyclodextrin (β-CD), on SBII was studied by various spectral methods.
The thermodynamic properties and stability of the inclusion complexes are studied by PM3 methods.
Evaluation of 2-pyrrolidone As a Potential Adjuvant in Self-Emulsifying Formulation for Oral Delivery of Poorly Water-Soluble Drugs
Solubilisation efficiency of Soluphor® P (2-pyrrolidone) for itraconazole was exploited for developing a self-emulsifying formulation. The objective of this study was to develop and evaluate self-emulsifying drug delivery system (SEDDS) for improving the delivery of a poorly water-soluble antifungal agent, itraconazole (ITZ). Phase diagrams were constructed at different
ratios of surfactant/co-surfactant (Km) to determine microemulsion existence region
In vitro and In vivo Comparison of Marine Magnesium salts (Oxide, Citrate, Bisglycinate, and Citrate Malate) Absorption and their Activity on Inflammatory Response and Oxidative Stress
Although dietary magnesium intake is common, its low bioavailability contributes to widespread deficiency in modern pop
ulations. This study aims to evaluate the absorption and biological activities of four marine magnesium forms (oxide, cit
rate, citrate malate, and bisglycinate) for maximizing magnesium biological effectiveness. Absorption of marine organic
magnesium compounds was compared to marine magnesium oxide by Caco-2 intestinal permeability assay and their in
vivo bioavailability in mice
