Editorial Board Member - JCSB
Yan Guo
Assistant ProfessorCenter for Quantitative Sciences
Vanderbilt University
United States
BIOGRAPHY:
I obtained my PhD from the Department of Computer Science, University of South Carolina, with focus on bioinformatics. Soon after my graduation, I became a research assistant professor at the Department of Cancer Biology, Vanderbilt University. Currently I am serving as the Technical Director of Bioinformatics for Vanderbilt Technologies for Advanced Genomics Analysis and Research Design (VANGARD), a core to consolidate the genomics data pipeline across Vanderbilt University by providing biostatistical and bioinformatic support for next-generation sequencing and other genomics technologies. Much of my research was related to bioinformatics with specific focus on methodology development around next-generation sequencing technologies. My second area of research interest is mitochondrial function and epigenetic biomarker identification in cancer.
RESEARCH INTERESTS:
Research on developing bioinformatics-specific methodologies, especially in cancer research, is my primary interest. I am also interested in mitochondrial function and epigenetic biomarker in caner. Much of my research time has focused on methodology development for next generation sequencing data analysis. My most recent research work was centered on the “lost treasures” of sequencing data. I am also interested in the quality control procedures for NGS data analysis.
Also of interest are topics such as mitochondria function in cancer research. For example, in 2011, we evaluated 44 DNA blood samples from 17 Danish and 1 Finnish families (18 mothers and 26 children) using NGS technology. All mothers had been treated for cancer as children and radiation doses to their ovaries were determined based on medical records and computational models. We sequenced their mitochondria genome in order to determine if any mutation damage to mother’s ovaries got carried to the offspring. The result of this study was published in Mutation Research.
Other Editorial Board Members - JCSB
Yu Shyr
Department of Biomedical Informatics
Vanderbilt University
United States
Yanni Sun
Department of Computer Science and Engineering
Michigan State University
United States
Vivek Tanavde
Bioinformatics Institute
Singapore
Valery Soyfer
Department of Molecular & Microbiology
George Mason University
United States
Tuan D. Pham
Aizu Research Cluster for Medical Engineering and Informatics
The University of Aizu
Japan
DON KULASIRI
Centre for Advanced Computational Solutions
Lincoln University
New Zealand
Josep Bassaganya-Riera
Virginia Bioinformatics Institute
United States
Petras Kundrotas
Center for Bioinformatics
The University of Kansas
United States
Erich J. Baker
Department of Computer Science
Baylor University
United States