Journal of Cancer Science and Clinical Oncology

Dr. Chunying Li is an Assistant Professor at Department of Biochemistry & Molecular Biology and Department of Oncology, as well as a Scientific Member at Barbara Ann Karmanos Cancer Institute and Cardiovascular Research Institute at Wayne State University School of Medicine in Detroit of Michigan. Dr. Li received his Ph.D. in Physiology at the University of Tennessee Health Science Center. His research has been well funded by grants from a variety of foundations and associations such as American Heart Association, Elsa U. Pardee Foundation, American Cancer Society, etc. Dr. Li has published highly-referred manuscripts in top-tier journals such as Cell, Journal of Experimental Medicine, PNAS, Journal of Biological Chemistry, Cancer Letters, Translational Oncology, PLoS ONE, etc. His research interest lies in the inflammation and cancer biology, with focus on defining the molecular mechanisms of chemokines and their receptors in cancer progression, tumor angiogenesis, inflammation, etc.

(1). To understand the macromolecular signaling complex of chemokine receptors (CXCR2, CXCR5, CX3CR1, etc) in various disease conditions:

• Pathological Angiogenesis (endothelial progenitor cell angiogenesis in ischemia, arterial injury, endothelial progenitor cell tumor angiogenesis in cancer)
• Tumorigenicity & Metastasis (pancreatic, prostate, and oral / head-neck cancers)
• Inflammation (immune cell response in cystic fibrosis and inflammatory bowel disease)

(2). To identify new therapeutic targets (in chemokine receptor signaling) & develop novel intervention strategies for disease prevention and treatment.