Editorial Board Member - JPDD
SANTAMARIA RITA
Associate ProfessorDepartment of Pharmacy
University of Naples Federico II
Italy
RESEARCH INTERESTS:
Dr Santamaria Rita's research interests have concerned the following fields: tRNA metabolism; cloning and sequencing of cDNA for human aldolase B and protein C; chromosomal mapping of Becker muscular dystrophy gene, protein C and aldolase isoenzymes genes. Other contributions have concerned the study of hereditary diseases, as hemophilia A and B and hereditary fructose intolerance (HFI). In particular, for the HFI many novel mutations disease-related have been identified and the relationship genotype/phenotype was studied.
Current research field regards the molecular mechanisms regulating cellular iron homeostasis. In this context has been studied in different physio-pathological conditions, the expression and activity of main proteins involved in the metabolism of this metal, such as ferritin, transferrin receptor and Iron Regulatory Proteins (IRPs). In particular were studied: the effects of oxalomalic acid on IRPs activity and ferritin biosynthesis; the regulation of iron metabolism in neuronal cells exposed to hypoxia/reoxigenation; the effects of Bovine Herpes Virus 1 (BHV-1) infection on iron homeostasis in Madin-Darby bovine kidney (MDBK) cells; the iron metabolism in rat adipose tissue after ovariectomy and estrogen treatment; the iron metabolism in a bovine cell line exposed to dioxin; the iron metabolism during BHV-1 infection in the presence of TCDD in mammalian cells.
Topics of research collaboration have been: neuroprotective effects of cannabidiol; effects of oxalomalic acid on iNOS; cytotoxic/cytoprotective effects of natural origin substances; effects of protein chemotactic for monocytes-3 on smooth muscle cells human coronary artery; protein translation in rat skeletal muscle cells.
Other Editorial Board Members - JPDD
Michael Zhuo Wang
Department of Pharmaceutical Chemistry
The University of Kansas
United States
James David Adams
Department of Pharmacology and Pharmaceutical Sciences
University of Southern California
United States
FRANCISCO FERNANDEZ CAMPOS
Department of Pharmaceutical Technology
University of Barcelona
Spain
NORMA RANGEL
Division of Graduate Studies and Research
Institute of Technology Aguascalientes (ITA)
Technological Institute of Aguascalientes (ITA)
Mexico
Carla Cicala
Department of Pharmacy
University of Naples Federico II
Italy
KAZI MOHSIN
Department of Pharmaceutics
King Saud University
Saudi Arabia
BADER MUBARAK W. AL-JAEID
King Abdulaziz University
Saudi Arabia
SUNLIANG CUI
College of Pharmaceutical Sciences
Zhejiang University
China
Emmanuel Ho
Department of Immunology
University of Manitoba
Canada
Michael P. Namaka
Faculty of Pharmacy and Medicine
University of Manitoba
Canada