ANNEX PUBLISHERS

Journal of Immunology and Infectious Diseases

Editorial Board Member - JIID

Lan Zhou

Assistant Professor
Department of Pathology
Case Western Reserve University
United States
BIOGRAPHY:

Dr. Zhou completed her PhD thesis studying the gap junction protein regulation by Src oncogene. From 1999 to 2001, Dr. Zhou worked as a Research Associate at HHMI under Dr. John Lowe’s supervision to study how fucosyl- glycans modify selectin ligand activity in myeloid cell homeostasis. Since being recruited to Case Western Reserve University, Dr. Zhou has conducted research to try to understand the functional regulation of hematopoietic stem cell (HSC) fate specification and differentiation, myeloid and lymphoid cell homeostasis, and HSC self-renewal and niche development by fucosylated glycans present on Notch and selectin ligands. Dr. Zhou has also been interested in the role of Notch signaling in pancreatic cancer and aberrant glycosylation in colon carcinogenesis and tumor surveillance. Her long term research goals include

 1) to understand the mechanism(s) of which Notch as a signaling molecule and an adhesion molecule in HSC niche retention and quiescence maintenance

 2) to identify cellular and/or soluble factors that are critical for suppression of hematopoiesisby leukemia cells that are amenable to disruption

 3) to develop a deeper understanding of the role of Notch signaling in pancreatic cancer progression

 4) to use mouse models to investigate the mechanisms of aberrant glycosylation induced colitis and colon cancer development.



RESEARCH INTERESTS:

Dr. Zhou long term research focus is to understand the normal hematopoietic stem cell (HSC) niche regulation by Notch and associated adhesion processes, how leukemia regulates marrow micro-environment, and the role of aberrant Notch signaling in pancreatic cancer and colon cancer carcinogenesis and immuno-surveillance.





Other Editorial Board Members - JIID

ALI AMIN

Assistant Professor
Warren Alpert Medical School
Brown University
United States

Jeffrey E. Lee

Assistant Professor
Laboratory Medicine & Pathobiology
University of Toronto
Canada

David L. Hirschberg

Assistant Professor
Columbia University
United States

Frank Portugal

Associate Professor
Department of Biology
The Catholic University of America
United States

Subash Sad

Professor
Department of Biochemistry, Microbiology and Immunology
University of Ottawa
Canada

Andrew Taylor-Robinson

Professor of Immunology & Haematology
School of Medical & Applied Sciences
Central Queensland University
Australia

Janet Liversidge

Professor
School of Medicine and Dentistry
University of Aberdeen Institute of Medical Sciences
United Kingdom

Daniel Lacorazza

Assistant Professor
Department of Pathology & Immunology
Baylor College of Medicine
United States

Martin Michaelis

Professor of Molecular Medicine
Centre for Molecular Processing and School of Biosciences
University of Kent
United Kingdom

Daniel Lacorazza

Associate Professor
Departments of Pathology and Immunology
Baylor College of Medicine
United States
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