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    Annex publishers is an Open Access publication model which allows the publication of articles to the world through this community. We provide you the asset of interaction with the most researchers from the scientific community. Anyone can freely access the articles printed under Annex publishers.
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    Open access provides an unlimited access to journals and publications, with a perfect platform for thousands of researchers to form jointly for the development of science. Open Access assists in accelerating the scientific discovery, encourage innovation, enhance education and refresh the economy to build up the knowledge of the general public.
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Recent Articles

A Case of Bulbar Amyotrophic Lateral Sclerosis with Mild Cognitive Impairment

It is still contentious whether amyotrophic lateral sclerosis (ALS)-Alzheimer’s disease (AD) cases comprise a combined disease or represent a coincidental association. We describe the case of a 78-year-old white male with a 12-month history of bulbar muscle weakness and mild cognitive impairment. Hallmarks of AD pathology were present and associated with diffuse congophilic angiopathy. The motor cortex did not show a loss of motoneurons. The anterior horns of the medulla oblongata and hypoglossal nuclei showed skein-like cytoplasmic inclusions and ubiquitin and TDP43 phosphate positive staining. No signs of FTLD were detected. The pathological results suggest that, in this case, ALS and AD pathology appeared to be independent.