Cardiovascular complications are the major cause of morbidity and mortality in diabetic patients. Pioglitazone (PIO) is used for the treatment of type 2 diabetes mellitus and there is some evidence that it may improve ventricular function in diabetic patients.
NIH Funded Articles
- Objectively Coding Intervention Fidelity During A Phone-Based Obesity Prevention Study
- Predictors of Obstructive Sleep Apnea Risk among Blacks with Metabolic Syndrome
- Wake-up Strokes Are Similar to Known-Onset Morning Strokes in Severity and Outcome
- Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites
- Acculturation and Subclinical Atherosclerosis among U.S. South Asians: Findings from the MASALA study
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Comparison of the Effect of Three Food Diets Provided to Giant Tortoises (Chelonoidis guntheri and Chelonoidis vicina) Bred in Captivity at Isabela Island – Galápagos
Digestive strategies are considered a key factor for healthy growth and conservation of the Galapagos symbol animal. In the breeding center of Isabela Island there is no nutrition studies on giant tortoise bred in captivity, which are exclusively fed with otoy, yautia or malanga (Xanthosoma sagitifolium). In the present study we worked with 60 juvenile tortoise of Galapagos (Chelonoidis guntheri and Chelonoidis vicina), divided into 3 groups of 20 animals each.
Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets
The purpose of this study is to synthesize and characterize nanodroplets, loaded with docetaxel for treatment of prostate cancer under MR-guided focused ultrasound. Water insoluble docetaxel encapsulated in nanodroplets is expected to be delivered into tumors with greater efficiency while minimizing drug related systemic toxicities when used in combination with focused ultrasound. The sequence of our studies toward development and characterization of docetaxel-loaded nanodroplets is as follows. First, we developed methods for synthesis of ultrasound-responsive, docetaxel-loaded nanodroplets (Doc-nd) by a solid dispersion technique. Secondly, we characterized Doc-nd by its morphology and size distributions using a dynamic light scattering (DLS) method.
With the discovery of osseointegration and advancement in dental materials dental implants provide superior support, stability and retention for prosthetic replacement of missing teeth than any available prosthetic option. But with the use of implants, an associated biological complication of peri-implant disease is seen in 48% of cases. Hence, this review aims to summarize the risk factors associated with peri-implantits and highlights current prevention strategies available and those to be further researched to minimise the incidence and severity of peri-implant disease and enhance longevity of implants.